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Spinal fusion involves joining two or more vertebrae to stabilize the spine and reduce pain

However, LepR GHR KO mice showed reduced body adiposity and serum leptin levels compared to control animals, whereas brain GHR KO mice had higher lean body mass and upregulation of hypothalamic GH-releasing hormone expression (GHRH

Additionally, certain peptides accelerate cell regeneration by encouraging the migration and growth of skin and connective tissue cells, allowing wounds to close more quickly

It is investigated in experimental models for its interaction with growth factor signaling, angiogenesis-related mechanisms, and cytoprotective processes